Commentary: A Primer on Human Brain Organoids for the Neurosurgeon
نویسندگان
چکیده
منابع مشابه
Translational potential of human brain organoids
The recent technology of 3D cultures of cellular aggregates derived from human stem cells have led to the emergence of tissue-like structures of various organs including the brain. Brain organoids bear molecular and structural resemblance with developing human brains, and have been demonstrated to recapitulate several physiological and pathological functions of the brain. Here we provide an ove...
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We developed an in vitro model system where induced pluripotent stem cells (iPSCs) differentiate into 3-dimensional human hepatic organoids (HOs) through stages that resemble human liver during its embryonic development. The HOs consist of hepatocytes, and cholangiocytes, which are organized into epithelia that surround the lumina of bile duct-like structures. The organoids provide a potentiall...
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ژورنال
عنوان ژورنال: Neurosurgery
سال: 2020
ISSN: 0148-396X,1524-4040
DOI: 10.1093/neuros/nyaa243